Exposure to air pollution may hasten brain aging, a new study has found.
一項新研討發明，裸露在氛圍汙染中大概會加快大腦朽邁。
Researchers studied 1,403 women without dementia who were initially enrolled in a large health study from 1996 to 1998. They measured their brain volume with magnetic resonance imaging scans in 2005 and 2006, when the women were 71 to 89.
這項研討的工具為1403名未患癡呆癥的女性，她們曾在1996年至1998年間介入過另外一項大型康健研討。在2005年和2006年，研討職員用磁共振成像掃描的方法，丈量了這些年事在71歲至89歲之間的女性的腦容量。
Using residential histories and air pollution data, they estimated their exposure to air pollution from 1999 to 2006. They used data recorded at monitoring sites on exposure to PM 2.5 — tiny particulate matter that easily penetrates the lungs.
研討職員應用棲身記載和氛圍汙染數據，對她們從1999年到2006年裸露在氛圍汙染中的情形舉行了估算。他們應用了監測PM 2.5的站點記載的數據。PM 2.5是一種輕易進入肺中的微粒物。
Each increase of 3.49 micrograms per cubic centimeter cumulative exposure to pollutants was associated with a 6.23 cubic centimeter decrease in white matter, the equivalent of one to two years of brain aging. The association remained after adjusting for many variables.
每立方厘米中積累汙染物每增長3.49微克，腦白質就會削減6.23立方厘米，相稱於大腦朽邁一到兩年。依據多個變量舉行了調劑後，這類相幹性仍然存在。
Previous studies have shown that air pollution can cause inflammation and damage to the vascular system, but this study, in The Annals of Neurology, showed damage to the brain itself.
以前的研討註解，氛圍汙染大概會致使血管體系發炎受損，而揭櫫在《神經學年報》(The Annals of Neurology)上的這項研討註解，氛圍汙染會致使大腦受損。
“This tells us that the damage air pollution can impart goes beyond the circulatory system,” said the lead author, Dr. Jiu-Chiuan Chen, an associate professor of preventive medicine at the Keck School of Medicine at the University of Southern California. “Particles in the ambient air are an environmental neurotoxin to the aging brain.”
“這告知咱們，氛圍汙染帶來的傷害不但限於輪回體系，”文章的第一作者、南加州大學凱克醫學院(Keck School of Medicine at the University of Southern California)防備醫學副傳授陳居泉(Jiu-Chiuan Chen)博士說。“對日漸朽邁的大腦來講，四周氛圍中的顆粒物是天然情況中的神經毒素。”
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